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Consistent with findings in animal experiments, GLP-1 alleviated Aβ-induced glycolytic suppression as demonstrated by the increased expression of glycolytic enzymes such as PKM2 and HK2 (Figure 4A) and enhanced glycolytic products (Figure 4B, Figure 4C, and Figure 4D)
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The standard titration schedule begins at 0.25 mg once weekly for four weeks, increasing to 0.5 mg, and potentially to 1 mg or 2 mg for optimal glycaemic control
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