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The review's conclusion: Health Canada did not find evidence to support a link between GLP-1 RAs and the risks of suicide, self-harm and suicidal/self-harm ideation in patients with type 2 diabetes, but there was not enough information to determine if there is a link in patients with obesity

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The UK Medicines and Healthcare products Regulatory Agency has stated GLP-1 medicines should not be taken during pregnancy or just before trying to get pregnant