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How dual GLP-1/GIP drugs work Explain what makes dual GIP/GLP-1 medications like tirzepatide mechanistically different from GLP-1-only drugs, and what that difference may mean clinically.
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Some of those risks are noteworthy despite GLP-1 RAs’ good track record in studies, including potential increases in thyroid cancer risk (seen only in animal studies) and the possibility of pancreatitis (seen in human studies).5 6 The decision to offer only testosterone cypionate or testosterone cream as low testosterone treatments when there are other, potentially safer, places for men to start dinged the company’s score here a bit.2 In our testing experience, we found it incredibly easy to get a GLP-1 RA prescription