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The Impact of GLP-1 Receptor Agonists (GLP-1 RAs) on Mental Health: A Systematic Review | Current Treatment Options in Psychiatry | Springer Nature Link
Some health care professionals and providers are more inclined to recommend the injectable option, expressing concern that real-world adherence to the pill’s rigid timing requirements may be challenging and could compromise effectiveness 2
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Despite the controversies about the expression of GLP-1R in vascular smooth muscle and endothelial cells, studies have shown that GLP-1RAs have anti-proliferative effects on these cells, and also reduced oxidative stress and increased the production of nitric oxide (NO) (137, 138)