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Obesity is also associated with a pro-inflammatory state marked by elevated levels of cytokines such as TNF-α, IL-6, and prostaglandin E2, which promote tumor proliferation, invasion, angiogenesis, and immune evasion [4,20]
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On the other hand, one company trial found that patients regained roughly 14% of their body weight within a year of stopping the drug.Even after the medicines stop reducing further, options like bariatric surgery remain off the table for many users, including Gaitonde and Anish
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