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In order to test the hypothesis that this increase in insulin secretion is in part mediated by the incretin glucagon-like peptide 1 (GLP-1), asymptomatic individuals with previous GB, 10 matched healthy nonoperated control subjects, and 12 patients with recurrent hypoglycemia after GB were examined with and without administration of the GLP-1 receptor antagonist exendin-(9-39)
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8 The Cleveland Clinic clarifies that while adjusting GLP-1 dosages is a common, safe practice for healthcare providers and patients under their strict supervision, microdosing compounded versions of GLP-1s—which are not FDA-approved—is a different practice with its own potential safety and quality risks
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