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Petersburg Institute of Bioregulation and Gerontology, it has been shown in research models to stimulate protein synthesis in testicular cells, modulate gene expression linked to steroidogenesis, influence stem cell differentiation into functional Leydig-lineage cells, and counteract age-related involution of reproductive tissues

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Although the researchers replicate a clinical trial finding of a reduction in heart attacks and strokes among patients with existing cardiovascular disease and chronic kidney disease and a reduction in moderate alcohol consumption risk, they find no statistically significant decline in broader emergency department visits or in any major diagnostic category