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2 The recommended time between dose increases is 3 to 4 days (the same amount of time it takes to reach steady state) 1 The Tresiba ® half-life is approximately 2X longer than insulin glargine U-100 2,4 42+ hour duration of action Tresiba ® U-100 is a basal insulin proven to last 42 hours—that won’t taper off at the end of the day 1,5-7,a A consistent routine is important, but if life gets in the way of a scheduled dose, Tresiba ® provides continued efficacy