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Use of the dual GIP/GLP-1 drug tirzepatide (Mounjaro, Zepbound) was associated with a significantly reduced risk of glaucoma compared with GLP-1 drugs among patients with type 2 diabetes, a large retrospective cohort
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This framework highlights that GLP-1RAs exert metabolic benefits extending beyond glucose regulation, acting as a mechanistic bridge between gut microbial dynamics and the integrated control of AT function and whole-body energy homeostasis [146,147]