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For type 2 diabetes management, the medication may be needed long-term as diabetes is a chronic condition requiring ongoing treatment, though some patients may be able to reduce or discontinue medication if significant weight loss and lifestyle modifications lead to remission of their diabetes
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In the context of risk of confounding by indication, propensity score matching was not expected to provide additional reduction of residual confounding beyond the applied covariate adjustment (psychiatric, somatic, and sociodemographic factors) and self-controlled analyses [33]
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