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is tirzepatide better tolerated than semaglutide Vs : r/GLP1ResearchTalk Subscription:6-months Health & Fitness Weight Akkermansia
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Whether GLP-1 RAs may worsen symptoms of common gastrointestinal conditions (e.g., inflammatory bowel disease, irritable bowel syndrome, gastroesophageal reflux) is unclear, but interaction is likely because of GLP-1’s pleiotropic effect on gastrointestinal functions
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The SURMOUNT-1 trial enrolled adults with obesity (or overweight with comorbidities) without diabetes and treated them with tirzepatide 5, 10, or 15 mg versus placebo for 72 weeks
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