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HoFH is a rare condition caused by a genetic mutation (an abnormal change in a gene) in the genes that control how your body clears cholesterol

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injection of d-glucose (1 or 2 g kg −1 , 10 ml kg −1 ), insulin (1.0 or 1.5 IU kg −1 , 10 ml kg −1 ) or sodium pyruvate (2 g kg −1 , 10 ml kg −1 ), and blood samples were collected at 15–240 min