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Nitration of tyrosine residues to form 3-nitrotyrosine (3-NT) alters protein structure and function, disrupting enzymatic activity and intracellular signaling
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ACSL5 , the major small intestinal acyl-coenzyme A (CoA) synthetase, mediates the initial step of dietary fat absorption within enterocytes by adding CoA to fatty acids, forming acyl-CoAs that are effectively trapped inside enterocytes 76
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