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This is due to OGT's substrate, UDP‐GlcNAc, which is a product of the hexosamine biosynthetic pathway (HBP) and is directly influenced by the influx of nutrients like glucose, glutamine, acetyl‐CoA, and uridine, meaning changes in nutrient availability can directly affect OGT activity
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Size:18 Servings
doi: 10.2337/dc10-1303