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Recent mechanistic work further showed that GLP-1R acts as a T cell–negative costimulatory molecule, providing direct support for the ability of GLP-1 signaling to restrain T-cell activation and immune-mediated injury [84]
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“It’s really hard to get a handle on the actual number of prescriptions and adverse events, including serious adverse events, among people who use compounded semaglutide and tirzepatide,” says Jody Dushay, MD, an endocrinologist and an assistant professor at Harvard Medical School and Beth Israel Deaconess Medical Center in Boston
