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More than 6 million patients in the US initiated GLP-1 use between 2021 and 2025. The proportion of prescriptions without documented clinical indications rose steadily over that time, reaching roughly 0.74% by
For thicker subcutaneous tissue, slightly longer needles ensure reliable subcutaneous rather than intradermal placement
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15,20 Although many of these AEs have occurred early in therapy and subsided over time, they remain a primary reason for dose adjustment or discontinuation
