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随着以索马鲁肽和替拉帕肽为代表的GLP-1受体激动剂类减肥药物的问世，肥胖症的治疗方式发生了翻天覆地的变化。这些药物在新加坡越来越受欢迎，成为医生处方治疗肥胖症及相关健康问题的常用选择。它们作用于影响食欲和新陈代谢的激素通路，在仅靠生活方式改变不足以控制肥胖的情况下，提供药物支持。

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These outcomes are likely attributable to a combination of mechanisms, including effects on hunger signals in the hypothalamus, which governs satiety and energy balance, though the relative contribution of each pathway has not been definitively established in humans