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dual gip/glp-1 receptor agonist GLP1-GIP co-agonists: a promising evolution in the treatment of type 2 diabetes | Acta Diabetologica Design of a novel long-acting –

Bifidobacterium longum, Lactobacillus rhamnosus

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Methods Insect cell expression HA-signal peptide-FLAG-3C-GLP-1R-3C-8×HIS 13 , human DNGα s 46 , His 6 -tagged human Gβ 1 and Gγ 2 were expressed in Tni insect cells (Expression systems) using baculovirus as previously described