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[2] [3] Based on the known class effects of GLP-1 and GIP receptor agonists, the following additional cautions are relevant, even where retatrutide-specific data are still emerging: Acute pancreatitis : Participants should be advised to seek urgent medical attention if they develop severe, persistent abdominal pain — particularly pain radiating to the back — accompanied by vomiting, as this may indicate pancreatitis
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Even before that, the complaint notes that reports filed with the FDA’s Adverse Event Reporting System (FAERS) linked incidents of “optic ischemic neuropathy” to GLP-1 use as early as 2012
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