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We used a composite outcome for our primary analysis that consisted of benign and malignant thyroid tumors given potential GLP-1RA effects on both seen in animal models

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Two phase 2 trials are currently active but not recruiting: NCT04305002 evaluates weekly exenatide (2 mg) with disease progression measured by FDG-PET and MDS-UPDRS III, while NCT04269642 is investigating PT320, a sustained-release formulation of exenatide (2.0 or 2.5 mg biweekly), in patients with early PD