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They’re approved for use alongside lifestyle changes, including increased physical activity and decreased caloric intake (usually eating 500 fewer calories per day)
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During an average follow-up of 26.3 months (2.2 years, SD 1.9 years), the annual rate of acute healthcare utilization was 1.52 visits/year in the GLP1-RA group and 1.67 visits/year within the DPP4i group (coefficient of regression β = −0.15, 95% CI −0.25 to −0.05, p = 0.004)