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“It's not just like, ‘Oh, use it for six months, get to your goal weight, and stop.’ If you stop it, there's a very high chance you will regain all of the weight you lost, if not more.” According to a 2022 study , most people gain back the majority of the weight they lost within one year of stopping semaglutide
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In a separate study, researchers compared the health records of more than 5,600 people with breast cancer who were getting chemotherapy and using GLP-1s with people with breast cancer who were getting chemo and not taking GLP-1s
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