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As described previously, ambient temperature and humidity range were set at 64–84 °F and 30–70%, respectively and lighting in the animal-holding rooms was maintained on a 12-h light–dark cycle 34
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Yet it seems the most important biological pathway altered by semaglutide is the "GLP-1R-AMPK-PFKFB3 axis," a cascade of compounds that affects how various cells produce energy
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