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To clarify the involved signalling pathways, cells were incubated with AICAR (0.5 mmol/L), compound C (10 μmol/L), exendin (9–39) (200 nmol/L) or H89 (10 μmol/L) for 30 min before other treatments
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Retatrutide activates the glucagon receptor in addition to the GIP and GLP-1 receptors that tirzepatide targets
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